ANALYSIS OF THE IMPACT OF HYPERTENSIVE DISORDERS THAT OCCURRED DURING PREGNANCY ON OBSTETRIC AND PERINATAL OUTCOMES IN NEWBORNS

Анотація

Preeclampsia is a polyetiological hypertensive disorder that occurs in pregnant women and is manifested by elevated blood pressure and proteinuria [1]. The International Society for the Study of Hypertension in Pregnancy (ISSHP) defines preeclampsia as a condition that manifests after the 20th week of pregnancy and is characterized by a combination of high blood pressure (SBP/DBP over 140/90 mmHg) and significant proteinuria (over 300 mg/day) [2]. This condition is extremely dangerous for both the mother and the fetus as it can lead to serious complications such as fetal growth retardation, severe fetal-placental hemodynamic disorders, premature labor, severe multi-organ insufficiency, and in severe cases, the development of eclampsia and even the death of the mother and fetus [3]. Despite the existence of a large number of fundamental studies, the pathogenesis of the development of preeclampsia remains ultimately undetermined.